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Microperimetry differences in macular sensitivity threshold between first and second tested eyes
Natacha B Junqueira1, Luiz H Lima2, Rodrigo B Ferreira1
1Department of Ophthalmology, Otorhinolaryngology and Head and Neck Surgery, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
Arquivos Brasileiros De Oftalmologia
|February 10, 2021
Summary
This study found that macular sensitivity thresholds in microperimetry tests may be higher in the second eye tested, especially in fast mode. Patient understanding of the examination can influence results.
Area of Science:
- Ophthalmology
- Visual Neuroscience
Background:
- Microperimetry is a key tool for assessing retinal sensitivity and fixation stability.
- Understanding factors that influence microperimetry results, such as eye testing order, is crucial for accurate clinical interpretation.
Purpose of the Study:
- To compare macular sensitivity thresholds and fixation stability between the right (first tested) and left (second tested) eyes in healthy individuals.
- To investigate the impact of testing order on microperimetry outcomes.
Main Methods:
- Thirty healthy participants were randomly assigned to two groups, undergoing microperimetry in either fast or expert mode.
- The right eye was consistently tested before the left eye in all participants.
- Fixation stability was evaluated using parameters P1 and P2 in the expert mode group.
Main Results:
- A statistically significant difference in mean macular sensitivity threshold was observed between the first and second tested eyes in the fast mode group (p=0.0415).
- Fixation stability showed an increase in the second tested eye (p=0.034), with a higher percentage of fixation points within the central macula.
- A negative correlation was found between the right eye's macular sensitivity threshold and examination duration.
Conclusions:
- Macular sensitivity thresholds may be elevated in the second tested eye, particularly when using the fast mode of microperimetry.
- Fixation stability appears to improve when the second eye is tested.
- Individual comprehension of the microperimetry examination process can impact test results.

