Related Experiment Video
Updated: Nov 17, 2025

08:32
Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models
Published on: March 1, 2015
21.7K
[Dysphagia in Multiple Sclerosis - an underestimated symptom?]
Carolin Eckardt1, Sabine Ulrike Vay2, Clemens Warnke2
1Kölner Dysphagiezentrum, Köln.
Fortschritte Der Neurologie-Psychiatrie
|February 11, 2021
Summary
Dysphagia, a disabling symptom in multiple sclerosis (MS), is often underestimated. Early diagnosis and management are crucial for improving the quality of life for individuals with MS.
Area of Science:
- Neurology
- Gastroenterology
Background:
- Multiple sclerosis (MS) affects approximately 240,000 individuals in Germany.
- Dysphagia is a significant, yet understudied, disabling symptom in MS patients, impacting quality of life.
Purpose of the Study:
- To review the scientific literature on MS-related dysphagia.
- To raise awareness of dysphagia symptoms and diagnostic tools.
- To improve dysphagia management and patient quality of life in MS.
Main Methods:
- A structured literature review was performed on the development, manifestation, diagnosis, and treatment of MS-related dysphagia.
- Included smaller studies and pilot projects due to a lack of class 1 evidence.
Main Results:
- Flexible Endoscopic Evaluation of Swallowing and Videofluoroscopic Swallowing Evaluation are key diagnostic tools.
- Reported dysphagia frequency in MS varies widely (38%-81%) due to differing methodologies.
- Dysphagia is underestimated by patients and physicians; only 30% of affected patients receive specific treatment.
Conclusions:
- Dysphagia is a prevalent and underestimated symptom in multiple sclerosis.
- Improved diagnostic awareness and utilization of tools like FEES and VFS are needed.
- Targeted treatment for MS-related dysphagia can enhance patient outcomes and quality of life.
More Related Videos
Related Concept Videos
Disorders of the Skeletal Muscle
1.4K
The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
1.4K
Deglutition
3.6K
Swallowing, otherwise known as deglutition, facilitates the transport of food from the mouth to the stomach. It is a multifaceted process that involves both the tongue and the muscles of the throat and esophagus. Saliva and mucus aid in this process, which takes approximately 4 to 8 seconds for semi-solid or solid food and around 1 second for liquids or very soft food.
Swallowing can be divided into three stages: the voluntary phase, the pharyngeal phase, and the esophageal phase. Although the...
Swallowing can be divided into three stages: the voluntary phase, the pharyngeal phase, and the esophageal phase. Although the...
3.6K
Esophageal Strictures-II: Clinical Features and Management
257
Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
257
Gastrointestinal Motility Disorders
800
Gastrointestinal or GI motility disorders are characterized by irregular gastrointestinal tract movements, disrupting food transit from the mouth to the anus. They are caused by damage or dysfunction in gut muscles or nerves. These disorders can cause symptoms such as severe constipation, diarrhea, abdominal pain, and swallowing difficulties. Disorders can affect any segment of the GI tract and range widely in severity, from common conditions like GERD to life-threatening conditions like...
800
Barrett Esophagus-II: Clinical Manifestations and Management
466
Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
466
Taste Buds and Receptors
3.7K
Gustation, or the sense of taste, is intrinsically linked to the anatomical structures located on the tongue. This organ's surface, along with the entirety of the oral cavity, is adorned with stratified squamous epithelium. Evident on the tongue are elevated structures known as papillae (singular = papilla), which house the mechanisms for the transduction of gustatory stimuli. Four distinct types of papillae exist, each identified by their unique morphological attributes: the circumvallate,...
3.7K

