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Updated: Nov 17, 2025
Determining Viral Disinfection Efficacy of Hot Water Laundering
Published on: June 21, 2022
A sprayable Acid-Oxidizing solution containing hypochlorous acid (AOS2020) efficiently and safely inactivates
Nadia Giarratana1, Balan Rajan2, Kannan Kamala2
1APR Applied Pharma Research S.A, 6828, Balerna, Switzerland. nadia.giarratana@apr.ch.
Introduction:
To eliminate the COVID-19 pandemic, the transmission of the virus SARS-CoV-2 among the population needs to be blocked and/or at least reduced. Upper respiratory tract viral loads are highest in the early stages of the disease, and high loads are associated with higher mortality rates. This study aims to evaluate the virucidal efficacy of AOS2020, a novel sprayable Acid-Oxidizing solution containing pure and stable hypochlorous acid (HClO), on human coronavirus SARS-Cov-2 in vitro, and the tolerability profile on nasal and oral mucosa suggesting to be a potential solution for upper respiratory hygiene.
Method:
Virucidal assays and intranasal and oral irritation tests were undertaken in accordance with relevant national and international guidance and methods.
Results:
In pre-clinical tests, the AOS2020, showed > 99.8% virucidal efficacy in < 1 min against SARS-Cov-2. The safety profile testing on both the nasal and oral mucosa indicates that AOS2020 is non-irritant.
Conclusion:
These initial results indicate that this product has the potential treatment to reduce viral load in the upper respiratory tract.
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