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Updated: Nov 17, 2025

A Direct Force Probe for Measuring Mechanical Integration Between the Nucleus and the Cytoskeleton
Published on: July 29, 2018
Comparative study of phacoemulsification parameters with and without nitinol filament nuclear disassembly
William F Wiley1, Shamik Bafna, Hercules D Logothetis
1From the Cleveland Eye Clinic, Cleveland, Ohio.
Purpose:
The purpose of this study was to evaluate the impact of nitinol microfilament lens disassembly using the miLOOP device on phacoemulsification parameters in routine cataract surgery.
Setting:
Private practice in Cleveland, Ohio.
Design:
Retrospective comparative consecutive case series.
Methods:
A chart review of consecutive cataract surgery cases in a single center operated by a single surgeon was conducted. Eyes were grouped by whether they underwent nitinol filament nuclear disassembly. Phacoemulsification energy, phacoemulsification time, and irrigation/aspiration (I/A) recorded during the operation were compared. Bilateral eyes were included only if the contralateral eye was in the opposite group.
Results:
A total of 212 eyes in 131 patients were eligible for analysis, including 81 subjects with both eyes. Most eyes (93%) had grade 2+ or 3+ nuclear sclerotic cataracts. A total of 102 eyes (48%) underwent nitinol filament nuclear disassembly preceding phacoemulsification. For all eyes, there was a 16% reduction in phacoemulsification energy, with a larger drop in grade 3+ eyes (-22%). Phacoemulsification and I/A times also reduced significantly (-19% and -37%, respectively, P < .02).
Conclusions:
Nitinol microfilament nuclear disassembly reduced total phacoemulsification energy and time during cataract surgery, particularly in severe cataracts.
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