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COVID-19 infection and stroke risk
Shaghayegh Sadeghmousavi1, Nima Rezaei2,3,4
1School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran1985717443, Iran.
Reviews in the Neurosciences
|February 13, 2021
Summary
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause neurological complications, including stroke. This study explores the mechanisms by which SARS-CoV-2 may lead to cerebrovascular events.
Area of Science:
- Neurology
- Infectious Diseases
- Cardiology
Background:
- Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, has diverse clinical manifestations.
- Beyond respiratory symptoms, SARS-CoV-2 exhibits neurotropic potential, leading to various neurological conditions.
- Stroke has been identified as a significant complication associated with COVID-19.
Purpose of the Study:
- To discuss stroke as a complication of COVID-19.
- To investigate the potential mechanisms underlying SARS-CoV-2-induced stroke.
Main Methods:
- Review of existing literature on COVID-19 and neurological complications.
- Analysis of reported cases of stroke in COVID-19 patients.
- Discussion of potential pathophysiological pathways.
Main Results:
- COVID-19 is associated with an increased risk of stroke.
- Potential mechanisms include hypercoagulability, endothelial dysfunction, and direct viral invasion.
- Neurological manifestations of SARS-CoV-2 are varied and can include cerebrovascular events.
Conclusions:
- Stroke is a critical neurological complication of SARS-CoV-2 infection.
- Understanding the mechanisms is crucial for prevention and management strategies.
- Further research is needed to elucidate the precise relationship between SARS-CoV-2 and stroke.
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