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Computer-aided technology for fabricating removable partial denture frameworks: A systematic review and meta-analysis
Mariana Domingues Pordeus1, Joel Ferreira Santiago Junior2, Helena Sandrini Venante3
1MSc student, Dental School of Bauru, FOB-USP - University of São Paulo, Octávio Pinheiro Brisolla, Jardim Brasil, Bauru, São Paulo, Brazil.
The Journal of Prosthetic Dentistry
|February 14, 2021
Summary
Computer-aided design and manufacturing (CAD-CAM) for removable partial denture (RPD) frameworks shows promising clinical performance and improved aesthetics. While research is limited, CAD-CAM offers a viable alternative to conventional techniques for RPD fabrication.
Area of Science:
- Dentistry
- Biomaterials Engineering
- Digital Manufacturing
Background:
- Lack of consensus on indications and clinical performance of computer-aided design and computer-aided manufacturing (CAD-CAM) for removable partial denture (RPD) frameworks.
- Need for systematic evaluation of CAD-CAM RPD manufacturing techniques and their clinical outcomes.
Purpose of the Study:
- To systematically review and meta-analyze the literature on CAD-CAM methods for RPD manufacturing.
- To evaluate the clinical performance of CAD-CAM fabricated RPD frameworks compared to conventional techniques.
Main Methods:
- Comprehensive literature search up to September 2019 in major databases (PubMed/MEDLINE, Web of Science, Cochrane Library, SciELO).
- Adherence to PRISMA Statement criteria; systematic review and meta-analysis registered in PROSPERO.
- Inclusion of both clinical and in vitro studies, analyzed separately based on PICO question: 'Do the CAD-CAM frameworks have similar performances to those fabricated by conventional techniques?'
Main Results:
- 15 articles selected from 358; clinical studies showed mean discrepancy of 184.91 μm (0% heterogeneity) for occlusal rests.
- Predominant materials: cobalt-chromium (Co-Cr) and polyetheretherketone (PEEK); Co-Cr required adjustments, PEEK offered better aesthetics.
- In vitro studies: additive manufacturing and indirect techniques showed no significant difference in performance (P=.455).
Conclusions:
- Limited clinical and in vitro research currently available on CAD-CAM RPD frameworks.
- Preliminary data suggest comparable fit and improved aesthetics with CAD-CAM compared to conventional methods.
- Further research is needed to establish definitive indications and performance benchmarks for CAD-CAM RPDs.

