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Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis
Published on: May 10, 2024
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[Sertraline-induced chronic eosinophilic pneumonia]
P Brancaleone1, O Descamps2, M Piquet1
1Service de pneumologie, centres hospitaliers Jolimont, 7100 La Louvière, Belgique.
Revue Des Maladies Respiratoires
|February 14, 2021
Summary
Sertraline, a common antidepressant, can cause chronic eosinophilic pneumonia. This case highlights the importance of considering drug-induced lung disease in patients with respiratory symptoms.
Area of Science:
- Pulmonology
- Pharmacology
- Internal Medicine
Background:
- Sertraline is a widely prescribed selective serotonin reuptake inhibitor for depression.
- Interstitial lung disease has been anecdotally linked to sertraline use.
Observation:
- A 69-year-old patient developed bilateral pneumonitis after 10 months of sertraline treatment.
- Infectious and autoimmune causes were ruled out; lung biopsy showed eosinophilic lung disease.
Findings:
- Sertraline was suspected as the cause of chronic eosinophilic pneumonia due to the insidious onset and resolution after drug discontinuation.
- The patient's respiratory symptoms and imaging findings normalized after stopping sertraline.
Implications:
- This case underscores the potential for sertraline to induce chronic eosinophilic pneumonia.
- Clinicians should consider drug-induced lung disease in differential diagnoses for patients presenting with unexplained pulmonary conditions.
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