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Updated: Aug 2, 2026

High Content Screening Analysis to Evaluate the Toxicological Effects of Harmful and Potentially Harmful Constituents (HPHC)
Published on: May 10, 2016
[The dose-effect relationship in connection with the study of the interaction of chemical carcinogens]
Abstract:
Problems arising in studies of the co-action of carcinogenic chemicals may be approached using mathematical models of dose-response dependence. It is shown that approximation of the dose-response dependence of chemical carcinogenesis co-factors can be obtained with the aid of a second-order polynomial. The planning of relevant experiments and studies of dose-response dependence models should be based on application of mathematical planning procedures, namely, second-order plans. Certain plans are recommended.
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