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Updated: Nov 17, 2025

Breath Collection from Children for Disease Biomarker Discovery
Published on: February 14, 2019
Overlooking the Obvious during the COVID-19 Pandemic: Dyspnoea with Asymmetric Breath Sounds in a Toddler
Heli Salmi1,2, Heini Harve-Rytsälä3, Paula Rautiainen2
1Paediatric Research Center, New Children's Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Insights
A toddler experienced acute respiratory distress, initially suspected to be COVID-19. Medical professionals overlooked foreign body aspiration, a common cause in toddlers, due to pandemic-related biases. Prompt diagnosis and removal of the obstruction resolved symptoms.
Area of Science:
- Pediatric Critical Care
- Emergency Medicine
- Infectious Disease
Background:
- The COVID-19 pandemic has raised concerns regarding secondary effects on pediatric health.
- Healthcare providers may exhibit diagnostic bias towards COVID-19, potentially overlooking other conditions.
Observation:
- A 20-month-old boy presented with acute respiratory distress, initially managed in a pediatric intensive care unit.
- Initial symptoms included elevated temperature, petechiae, and asymmetrical pulmonary findings, leading to a pneumonia and SARS-CoV-2 (COVID-19) suspicion.
Findings:
- Foreign body aspiration of cashew nuts in the left bronchial tree was identified as the cause of respiratory distress.
- Bronchoscopic removal of the foreign body led to rapid and complete symptom resolution.
Implications:
- This case highlights the risk of diagnostic overshadowing due to the COVID-19 pandemic, even in pediatric cases.
- Emergency care providers must maintain a broad differential diagnosis for acute respiratory distress in children, avoiding biases.
- Alternative diagnoses, such as foreign body aspiration, should be considered promptly in pediatric respiratory distress cases.
Background:
Paediatric healthcare specialists are concerned about the secondary effects of the COVID-19 pandemic on children. We report a case of acute respiratory distress in a healthy toddler whose healthcare providers were sidetracked from the correct diagnosis by suspicion of COVID-19. Case Presentation. The patient was a 20-month-old healthy boy. In the morning, he had coughed while drinking milk. He was asymptomatic for the day but presented with acute respiratory distress when lying down in the evening. An ambulance was called, and he was taken to a tertiary hospital's paediatric emergency department, where his condition and oxygen saturation fluctuated. He had mildly elevated temperature and petechiae on his trunk, showed asymmetrical radiographic and auscultatory pulmonary findings, and did not tolerate any exertion. Pneumonia was suspected, SARS-CoV-2 was considered as potential causative agent, and the child was admitted to a Paediatric Intensive Care Unit. As the patient did not show clear signs of infection or bronchial obstruction, the events were thoroughly rediscussed with the caregiver next morning. It was then found out that the child had also been eating cashew nuts. Multiple pieces of cashew nuts were removed from the left bronchial tree in a bronchoscopy. After the procedure, all symptoms promptly resolved. Foreign body aspiration-an obvious cause of acute respiratory distress in our patient's age group-was overlooked by experienced emergency medical care providers and paediatric critical care physicians due to the slightly unusual presentation, incomplete anamnestic information, and a bias to consider COVID-19 in the current exceptional circumstances.
Conclusions:
Emergency care providers are instructed to consider all patients with respiratory distress as potential COVID-19 patients. However, the clinical course of COVID-19 infection is usually mild in children. Therefore, alternative causes for serious breathing difficulty are more likely, and all differential diagnoses should be considered in the usual unbiased manner.
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