Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Olfactory Receptors: Location and Structure01:03

Olfactory Receptors: Location and Structure

10.5K
The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
10.5K
Olfaction01:25

Olfaction

46.9K
The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...
46.9K
Physiology of Smell and Olfactory Pathway01:20

Physiology of Smell and Olfactory Pathway

10.9K
Humans detect odors with the help of specialized cells located in the upper part of the nasal cavity, called olfactory receptor neurons (ORNs). ORNs possess hair-like structures called cilia, which are receptive to sensations from the inhaled air. When an odorant molecule binds to a specific receptor on the cell of the cilia, it leads to a series of events that ultimately cause the ORN to send electrical signals to the olfactory bulb in the brain through the olfactory nerves.
The olfactory...
10.9K
Sputum Studies II: Culture and Sensitivity01:20

Sputum Studies II: Culture and Sensitivity

827
Description
Sputum culture and sensitivity is a medical procedure used to diagnose bacterial infections in the respiratory tract and select the most appropriate antibiotics for treatment. This process involves analyzing sputum samples of thick and opaque secretions produced in the lungs and airways. These samples are collected from patients and then sent to the laboratory for analysis.
The test can identify various pathogens responsible for respiratory infections, including Streptococcus,...
827

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Biochemical rationale for dietary management of COVID-19 patients: Indian traditional millets as a promising integrative nutritional strategy.

Journal of Ayurveda and integrative medicine·2026
Same author

Disability-related barriers to dental care among older Canadian adults: the role of sex as an effect modifier.

Frontiers in oral health·2026
Same author

Artificial intelligence for automated classification of antinuclear-antibody indirect immunofluorescence patterns.

EULAR rheumatology open·2026
Same author

Pulmonary Paragonimiasis Presenting as Pneumothorax, Hemoptysis, and Severe Eosinophilia: A Case Report.

Case reports in infectious diseases·2026
Same author

Isolated Palmar Hyperpigmentation: Rare Presentation of B12 Deficiency.

Clinical case reports·2026
Same author

Wafer-like calcification of the spine in ochronosis.

The National medical journal of India·2026

Related Experiment Video

Updated: Nov 17, 2025

A Free-breathing fMRI Method to Study Human Olfactory Function
10:42

A Free-breathing fMRI Method to Study Human Olfactory Function

Published on: July 30, 2017

9.9K

Olfactory Dysfunction Among Asymptomatic Patients with SARS CoV2 Infection: A Case-Control Study.

Vishal Mangal1, T Murari1, Rohit Vashisht1

  • 1Department of Internal Medicine, Armed Forces Medical College, Pune, Maharashtra 411040 India.

Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India
|February 15, 2021
PubMed
Summary

Olfactory dysfunction, including smell loss, is common in COVID-19. This study found impaired smell thresholds in both asymptomatic and mild COVID-19 patients compared to controls, though the Butanol Threshold Test couldn't differentiate asymptomatic cases.

Keywords:
AsymptomaticButanol threshold testingCOVID-19Olfactory dysfunctionSARS CoV2

More Related Videos

Author Spotlight: Assessing the Olfactory Effects of Airborne Pollutants — Buried Food and Social Odor Tests
04:00

Author Spotlight: Assessing the Olfactory Effects of Airborne Pollutants — Buried Food and Social Odor Tests

Published on: September 13, 2024

1.1K
Quantification and Whole Genome Characterization of SARS-CoV-2 RNA in Wastewater and Air Samples
09:26

Quantification and Whole Genome Characterization of SARS-CoV-2 RNA in Wastewater and Air Samples

Published on: June 30, 2023

1.4K

Related Experiment Videos

Last Updated: Nov 17, 2025

A Free-breathing fMRI Method to Study Human Olfactory Function
10:42

A Free-breathing fMRI Method to Study Human Olfactory Function

Published on: July 30, 2017

9.9K
Author Spotlight: Assessing the Olfactory Effects of Airborne Pollutants — Buried Food and Social Odor Tests
04:00

Author Spotlight: Assessing the Olfactory Effects of Airborne Pollutants — Buried Food and Social Odor Tests

Published on: September 13, 2024

1.1K
Quantification and Whole Genome Characterization of SARS-CoV-2 RNA in Wastewater and Air Samples
09:26

Quantification and Whole Genome Characterization of SARS-CoV-2 RNA in Wastewater and Air Samples

Published on: June 30, 2023

1.4K

Area of Science:

  • Otorhinolaryngology
  • Infectious Diseases
  • Neurology

Background:

  • Olfactory dysfunction is a known symptom of coronavirus disease-19 (COVID-19).
  • Limited research exists on olfactory dysfunction in asymptomatic COVID-19 patients.
  • Objective assessment tools are needed to evaluate smell dysfunction.

Purpose of the Study:

  • To investigate olfactory dysfunction in asymptomatic COVID-19 patients.
  • To compare olfactory function in asymptomatic COVID-19, mild COVID-19, and healthy controls.
  • To utilize objective assessment tools for smell evaluation.

Main Methods:

  • Recruited 57 male participants each for mild COVID-19, asymptomatic COVID-19, and control groups.
  • Assessed smell threshold using the Butanol Threshold Test (BTT).
  • Evaluated odor identification using the Smell Identification Test.

Main Results:

  • Significant differences in BTT scores were observed across the three groups (p < 0.005).
  • Mild COVID-19 and asymptomatic COVID-19 groups showed significantly lower BTT scores than controls (p < 0.005).
  • BTT scores did not differentiate between asymptomatic COVID-19 patients and controls.

Conclusions:

  • Smell threshold impairment is present in both asymptomatic and mild COVID-19.
  • Objective smell tests are crucial for identifying olfactory dysfunction in COVID-19.
  • Further research is needed to understand the nuances of olfactory dysfunction in asymptomatic COVID-19.