Cervicovaginal psammoma bodies. The initial presentation of the ovarian borderline tumor

Psammoma bodies associated with cancer cells of ovarian and endometrial origins have been previously described in cervicovaginal smears, as have psammoma bodies from totally benign processes. We describe the presence of numerous psammoma bodies in the cervical smear, endometrial curettage, and peritoneal wash specimens from a patient with subsequently discovered bilateral, ovarian, borderline serous tumors. We morphologically traced the transit of these psammoma bodies and their associated cytologically benign tumor cells through the entire female genital tract.