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Postoperative spindle-cell nodule of the endometrium
1Department of Pathology, Vancouver General Hospital, British Columbia, Canada.
Archives of Pathology & Laboratory Medicine
|May 1, 1988
Summary
A rare postoperative spindle-cell nodule was identified in the endometrium, a site previously undescribed for this lesion. This benign finding mimics sarcoma but is a reparative proliferation of fibroblastic cells.
Area of Science:
- Gynecologic Pathology
- Surgical Pathology
Background:
- Postoperative spindle-cell nodules (PSCNs) are typically found in the genitourinary tract.
- These lesions represent reactive proliferations of fibroblastic-type cells.
Observation:
- A case of PSCN occurred within the endometrium of a 75-year-old woman.
- The nodule was discovered in a hysterectomy specimen 2.5 weeks after a dilatation and curettage for endometrial adenocarcinoma.
Findings:
- Histologic examination revealed a densely cellular proliferation of mitotically active spindle cells.
- The endometrial lesion was initially misdiagnosed as sarcoma.
Implications:
- This report describes a novel site for PSCN, expanding the known locations of this entity.
- Distinguishing PSCN from sarcoma is crucial for accurate diagnosis and appropriate patient management.