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Bhavesh D Kevadiya1, Jatin Machhi1, Jonathan Herskovitz1,2

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Rapid diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is crucial. This review clarifies available and emerging diagnostic tests, including nanomaterial-based tools, for scientists and healthcare professionals.

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Area of Science:

  • Virology
  • Diagnostic Technologies
  • Nanotechnology

Background:

  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes COVID-19, a global pandemic with diverse symptoms.
  • COVID-19 diagnosis can be challenging due to similarities with influenza and other respiratory infections.
  • Accurate and rapid diagnostic methods are essential for effective treatment and containment.

Purpose of the Study:

  • To provide a comprehensive overview of current and developing diagnostic tests for SARS-CoV-2.
  • To highlight the role of nanomaterial-based tools in SARS-CoV-2 diagnostics.
  • To serve as a resource for researchers, clinicians, and the public.

Main Methods:

  • Review of existing literature on SARS-CoV-2 diagnostic strategies.
  • Inclusion of information on both commercially available and in-development diagnostic platforms.
  • Focus on emerging technologies, particularly those utilizing nanomaterials.

Main Results:

  • A wide array of diagnostic tests for SARS-CoV-2 are available and under development.
  • Nanomaterial-based diagnostics offer promising advancements in sensitivity and speed.
  • The review categorizes and describes various testing methodologies.

Conclusions:

  • Timely and accurate diagnosis of SARS-CoV-2 is critical for managing the pandemic.
  • Nanotechnology holds significant potential for improving future diagnostic capabilities.
  • This review consolidates essential information on SARS-CoV-2 diagnostics for diverse audiences.