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Lumpy skin disease in Kazakhstan
Mukhit B Orynbayev1,2, Raikhan K Nissanova3,4, Berik M Khairullin3
1RGE 'Research Institute for Biological Safety Problems', Committee of Science, The Ministry of Education and Science of the Republic of Kazakhstan, Gvardeiskiy, Zhambyl Region, Republic of Kazakhstan. omb65@mail.ru.
Tropical Animal Health and Production
|February 16, 2021
Summary
Lumpy skin disease (LSD) first emerged in Kazakhstan in 2016, affecting cattle and spreading via ticks and insects. This study confirmed the causative agent as lumpy skin disease virus (LSDV) through PCR and virus isolation.
Area of Science:
- Veterinary Virology
- Epidemiology
- Molecular Biology
Background:
- Lumpy skin disease (LSD) is a significant transboundary viral disease affecting cattle.
- The first outbreak of LSD in Kazakhstan was recorded in July 2016.
Purpose of the Study:
- To identify the causative agent of the lumpy skin disease outbreak in Kazakhstan.
- To investigate the role of arthropods in the transmission of LSDV in the affected region.
Main Methods:
- Polymerase chain reaction (PCR) was used to detect LSDV DNA in animal and arthropod samples.
- Virus isolation and propagation were performed in LT and MDBK cell cultures.
- Gene sequencing of the GPCR gene was conducted for viral identification.
Main Results:
- LSDV DNA was detected in cattle, ticks (Dermacentor marginatus, Hyalomma asiaticum), horseflies (Tabanus bromius), and Stomoxys calcitrans.
- A reproductive LSD virus was isolated from cattle and insect samples.
- The isolated virus was identified as LSDV through gene sequencing.
Conclusions:
- The study confirms the presence and spread of lumpy skin disease virus in Kazakhstan.
- Arthropods, particularly ticks, play a role in the transmission of LSDV in the region.
- This finding is crucial for understanding and controlling LSD outbreaks in Kazakhstan and surrounding areas.
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