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Homogeneous Gold-Catalyzed Oxidation Reactions.
Zhitong Zheng1, Xu Ma1, Xinpeng Cheng1
1Department of Chemistry and Biochemistry, University of California, Santa Barbara, California 93106, United States.
Chemical Reviews
|February 16, 2021
Summary
Oxidative gold catalysis has rapidly advanced, offering valuable synthetic methods. This review details these methods, organized by oxidation states and oxidants.
Area of Science:
- Catalysis
- Organometallic Chemistry
- Synthetic Organic Chemistry
Background:
- Homogeneous gold catalysis has seen significant growth since 2000.
- Oxidative gold catalysis is a key area within this field.
- It provides diverse and valuable synthetic methodologies.
Purpose of the Study:
- To comprehensively review oxidative gold catalysis.
- To organize discussions by mechanistic aspects, focusing on metal oxidation states.
- To categorize methods by oxidants and oxidizing functional groups.
Main Methods:
- Review of mechanistic aspects of gold oxidation states.
- Classification of methods based on oxidants.
- Analysis of synthetic applications.
Main Results:
- Detailed overview of oxidative gold catalysis.
- Categorization based on mechanistic pathways.
- Highlighting synthetic utility.
Conclusions:
- Oxidative gold catalysis is a well-developed field.
- The review provides a structured understanding of its methods.
- It emphasizes the practical value for synthetic chemists.
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