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Updated: Nov 17, 2025

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans

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Diagnosing coronary thrombosis using multiphase post-mortem CT angiography (MPMCTA): A case study.

Camatti Jessika¹, Santunione Anna Laura¹, Draisci Stefano²

¹Department of Biomedical, Metabolic and Neural Sciences, Institute of Legal Medicine, University of Modena and Reggio Emilia, Modena, Italy.

Medicine, Science, and the Law

|February 16, 2021

Summary

Post-mortem CT angiography (MPMCTA) accurately identified coronary thrombosis in a deceased individual, matching autopsy findings. This case highlights MPMCTA

Keywords:

Post-mortem angiography coronary thrombosis forensic radiology sudden cardiac death

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Retrograde Perfusion and Filling of Mouse Coronary Vasculature as Preparation for Micro Computed Tomography Imaging

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Published on: February 10, 2012

Area of Science:

Forensic Radiology
Medical Imaging
Pathology

Background:

Post-mortem angiography (PMA) is emerging in forensic radiology, but its application in Italian criminal proceedings requires further validation.
Limited literature exists on the systematic implementation of PMA techniques in Italy.
This study aims to address this gap by presenting a case utilizing multiphase post-mortem CT angiography (MPMCTA).

Observation:

A case involving a previously healthy 51-year-old male was investigated.
MPMCTA, autopsy, histology, and toxicology analyses were performed.
MPMCTA revealed a filling defect in the right coronary artery.

Findings:

MPMCTA successfully detected a right coronary artery filling defect consistent with acute coronary thrombosis.
Autopsy and histological examinations confirmed the presence of coronary thrombosis.
There was strong concordance between MPMCTA findings and the reference standard (autopsy and histology).

Implications:

This case supports the systematic implementation of MPMCTA in forensic investigations.
MPMCTA can serve as a valuable, non-invasive tool for diagnosing causes of death, particularly cardiovascular events.
The findings encourage broader adoption of PMA techniques in legal and forensic contexts in Italy.