Related Experiment Video
Updated: Nov 17, 2025
03:27
The Role of Indocyanine Green Fluorescence in Complex Laparoscopic Cholecystectomy Navigation
Published on: January 31, 2025
904
Possible dulaglutide-associated cholecystitis with safe continuation post cholecystectomy.
Jared Butler1,2, Marysue Bjurstrom2, Anna Marceau2
1Drake University, Des Moines, IA.
Summary
This case study discusses a patient who developed cholecystitis while on dulaglutide for type 2 diabetes. After gallbladder removal, dulaglutide was resumed without complications, suggesting it may be safe for long-term use.
Area of Science:
- Endocrinology
- Gastroenterology
Background:
- Dulaglutide is a glucagon-like peptide-1 receptor agonist used for type 2 diabetes management.
- Effective glycemic control is crucial for preventing diabetes-related complications.
Observation:
- A 72-year-old male on dulaglutide experienced acute cholecystitis after 16 months of treatment.
- The patient underwent cholecystectomy for a gangrenous gallbladder.
Findings:
- Post-cholecystectomy, dulaglutide was restarted without recurrence of biliary issues or abdominal symptoms.
- Glycemic control (HbA1c) improved with dulaglutide and was maintained post-operatively.
Implications:
- Dulaglutide may be safely resumed after cholecystectomy in select patients.
- This case highlights the importance of considering drug-induced adverse events in diabetes management.
Related Concept Videos
01:17Gallbladder
1.4K
The gallbladder is a small, pear-shaped organ that plays a crucial role in our digestive system. Measuring about 10 cm in length, it is comparable in size to a kiwi fruit and is located in a hollow area on the lower surface of the liver. The gallbladder's primary function is to store and concentrate bile, a fluid produced by the liver that aids in digestion.
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins...
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins...
1.4K
01:26Diseases of the Liver and Gallbladder
1.6K
Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
1.6K
01:29Chronic Pancreatitis II: Collaborative Care
178
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
Assessment:
178
01:30Acute Pancreatitis II: Clinical Manifestations and Management
424
Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
424
01:21Inflammatory Bowel Disease V: Surgical Management
302
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Here are some common surgical interventions for IBD:
302
01:24Drugs for Peptic Ulcer Disease: Sucralfate as Mucosal Protective Agents
966
In the intricate landscape of the gastric lumen, excessive acid secretion disrupts the natural defense mechanisms, weakening the mucus-bicarbonate barrier. This vulnerability allows pepsin to infiltrate epithelial cells, digesting mucosal proteins and triggering erosion, leading to ulcer formation.
In this scenario, mucosal protective agents like sucralfate play an essential role. Sucralfate, a complex of sulfated sucrose and aluminum hydroxide, demonstrates its usefulness in acidic conditions,...
In this scenario, mucosal protective agents like sucralfate play an essential role. Sucralfate, a complex of sulfated sucrose and aluminum hydroxide, demonstrates its usefulness in acidic conditions,...
966