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Updated: Nov 17, 2025
05:12
Portable Thermographic Screening for Detection of Acute Wallenberg's Syndrome
Published on: September 19, 2019
6.8K
Clinical picture: SDHD paraganglioma presenting with syncope
David P LaChance1, Thanh D Hoang1, Mohamed K M Shakir1
1Division of Endocrinology Department of Medicine Walter Reed National Military Medical Center Bethesda MD USA.
Clinical Case Reports
|February 18, 2021
Summary
This report details an unusual case of a rare condition, emphasizing comprehensive patient evaluation for diagnosis and surgical planning. It shows nonsecreting paragangliomas can arise from mass effects.
Area of Science:
- Oncology
- Surgical Pathology
Background:
- Paragangliomas are rare neuroendocrine tumors originating from extra-adrenal chromaffin cells.
- Nonsecreting paragangliomas present diagnostic challenges due to lack of specific hormonal markers.
Purpose of the Study:
- To describe an atypical presentation of a rare nonsecreting paraganglioma.
- To underscore the significance of a systematic diagnostic approach in rare tumors.
- To illustrate paraganglioma as a secondary diagnosis due to mass effect.
Main Methods:
- Case report detailing a patient with an atypical paraganglioma presentation.
- Review of medical history, family history, physical examination findings.
- Analysis of diagnostic investigations and perioperative workup.
Main Results:
- An atypical presentation of a rare nonsecreting paraganglioma was identified.
- The case highlights the importance of thorough clinical evaluation and diagnostic workup.
- Mass effect was identified as a potential cause for this rare tumor.
Conclusions:
- A comprehensive diagnostic algorithm including history, examination, and investigations is crucial for rare conditions.
- Nonsecreting paragangliomas, though rare, can manifest secondary to mass effects.
- This case emphasizes the need for vigilance in diagnosing rare tumors with unusual presentations.
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