Expectant Management of Severe COVID-19 Pneumonia in Late Preterm Pregnancy and Subsequent Cholecystitis: Lessons

Neggin B Mokhtari1, Daphnie Drassinower2, Lindsey A Orr3

  • 1Department of Obstetrics and Gynecology, MedStar Washington Hospital Center/Georgetown University, Washington, District of Columbia.

AJP Reports
|February 18, 2021
PubMed

Insights

Delaying delivery is a viable option for pregnant women with severe coronavirus disease 2019 (COVID-19), even in late gestation. A multidisciplinary approach ensures optimal outcomes for both mother and fetus during COVID-19 infection management.

Area of Science:

  • Obstetrics and Gynecology
  • Infectious Diseases
  • Critical Care Medicine

Background:

  • Pregnant women with COVID-19 face increased risks of hospitalization and severe outcomes.
  • Optimal delivery timing for pregnant patients with COVID-19, particularly in late preterm and early term gestation, remains unclear.
  • COVID-19 infection alone is not considered a sole indication for delivery in pregnant individuals.

Observation:

  • A case report details a pregnant patient in late third-trimester gestation with severe COVID-19.
  • The patient was managed expectantly, showing respiratory improvement without requiring delivery.
  • Cholecystitis developed during hospitalization, potentially representing a novel clinical association with COVID-19.

Findings:

  • Expectant management and delaying delivery can be a safe option for maternal stabilization in severe COVID-19 cases, even in advanced gestation.
  • A multidisciplinary team approach is crucial for managing pregnant women with COVID-19 to achieve optimal maternal and fetal outcomes.
  • COVID-19 infection may be associated with other clinical sequelae, such as cholecystitis.

Implications:

  • This case suggests that delaying delivery is a reasonable strategy for maternal stabilization in severe COVID-19 during late pregnancy.
  • Highlights the necessity of a collaborative, team-based approach in managing pregnant patients with COVID-19.
  • Suggests a potential link between COVID-19 infection and the development of cholecystitis in pregnancy.

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