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Chromosome abnormalities in peripheral blood lymphocytes from untreated Hodgkin's patients. A possible evidence for
L Barrios1, M R Caballín, R Mirò
1Departament de Biologia Cel.lular i Fisiologia, Universitat Autònoma de Barcelona, Bellaterra, Spain.
Human Genetics
|April 1, 1988
Abstract:
We describe the presence of a high frequency of spontaneous chromosome aberrations in lymphocytes from six untreated patients with Hodgkin's disease. The characteristics of the chromosome abnormalities observed suggest the existence of a certain degree of chromosome instability in these cases, that could be a predisposing factor for the development of malignancies.