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Venous sinus thrombosis during COVID-19 infection in pregnancy: a case report

Zahide Betül Gunduz1

  • 1MD, PhD. Neurologist and Assistant Professor, Department of Neurology, University of Health Sciences, Konya Education and Research Hospital, Konya, Turkey.

Sao Paulo Medical Journal = Revista Paulista De Medicina
|February 19, 2021
PubMed

Insights

A pregnant woman with COVID-19 developed venous sinus thrombosis, presenting with headache and hemiparesis. This case highlights the need to consider cerebral venous sinus thrombosis in COVID-19 patients with atypical neurological symptoms.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Obstetrics

Background:

  • The novel coronavirus disease (COVID-19), originating in Wuhan, China, primarily affects the respiratory system.
  • However, emerging information reveals a broad clinical spectrum of COVID-19 manifestations.
  • This includes neurological complications beyond the respiratory tract.

Observation:

  • A case report details a pregnant woman diagnosed with cerebral venous sinus thrombosis (CVST).
  • Her symptoms included headache and hemiparesis.
  • She tested positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) via polymerase chain reaction (PCR) for two weeks post-diagnosis.

Findings:

  • The patient presented with neurological deficits suggestive of a cerebrovascular event.
  • Cerebral venous sinus thrombosis was confirmed as the diagnosis.
  • Persistent PCR positivity indicated ongoing viral shedding.

Implications:

  • Cerebral venous sinus thrombosis should be considered in the differential diagnosis of COVID-19 patients, particularly those with hypercoagulability risk factors.
  • Atypical neurological presentations in COVID-19 necessitate a high index of suspicion for CVST.
  • Early recognition and management of CVST in COVID-19 patients are crucial for improved outcomes.
Abstract

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