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Fundamental Statistical Concepts in Clinical Trials and Diagnostic Testing

Stephanie L Pugh1, Pedro A Torres-Saavedra2

  • 1NRG Oncology Statistical and Data Management Center, American College of Radiology, Philadelphia, Pennsylvania pughs@nrgoncology.org.

Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
|February 20, 2021
PubMed
Summary

This article explains fundamental statistical concepts for clinical trial design and diagnostic tests. It covers hypothesis formulation, error types (Type I and Type II), and key performance metrics like sensitivity and specificity.

Keywords:
diagnostic testinghypothesis testingmultiplicityreceiver-operating-characteristic curves

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