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COVID-19: Diagnostics, Therapeutic Advances, and Vaccine Development
Sabhiya Majid1, Mosin S Khan1, Samia Rashid2
1Department of Biochemistry, Government Medical College Srinagar and Associated SMHS and Super Speciality Hospital and Research Centre, University of Kashmir Srinagar, Srinagar, J&K 190010 India.
Current Clinical Microbiology Reports
|February 22, 2021
Summary
The global response to the COVID-19 pandemic involved extensive monitoring and containment of SARS-CoV-2. While few antiviral treatments are approved, rapid vaccine development has yielded promising results.
Area of Science:
- Virology
- Epidemiology
- Public Health
Background:
- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes COVID-19, a global pandemic.
- Coronaviruses (CoVs) represent a significant public health challenge.
- Global efforts focus on monitoring, containment, and treatment of SARS-CoV-2.
Purpose of the Study:
- To review the global response to the COVID-19 pandemic.
- To highlight research on therapeutic agents and vaccines for SARS-CoV-2.
- To discuss diagnostic options and vaccine development.
Main Methods:
- Review of scientific literature on COVID-19.
- Analysis of therapeutic strategies and drug targets.
- Examination of vaccine development and diagnostic approaches.
Main Results:
- Limited approved antiviral treatments for SARS-CoV-2, with remdesivir being an exception.
- Identification of novel drug targets for potential therapies.
- Successful and rapid development of numerous promising COVID-19 vaccine candidates, with some receiving emergency use authorization.
Conclusions:
- The COVID-19 pandemic has had severe impacts on health and livelihoods.
- Significant scientific and healthcare worker efforts have been crucial in addressing the pandemic.
- Ongoing research into therapeutics, diagnostics, and vaccines continues to be vital.
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