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Published on: September 27, 2024
Elimination of macrophage-entrapped antibiotic-resistant bacteria by a targeted metal-organic framework-based
Xuemeng Liu1, Qingqing Deng1, Lu Zhang2
1Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China. dongkai@ciac.ac.cn jren@ciac.ac.cn xqu@ciac.ac.cn and University of Science and Technology of China, Hefei, Anhui 230026, China.
Abstract:
A novel metal-organic framework-based platform was designed and constructed for photosensitizer delivery for the elimination of intracellular antibiotic-resistant bacteria. With the merit of targeting and internalizing ability, the system could kill the stealthy bacteria efficiently under light irradiation.
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