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Updated: Nov 16, 2025

Measurement of Fronto-limbic Activity Using an Emotional Oddball Task in Children with Familial High Risk for Schizophrenia
Published on: December 2, 2015
[Psychopathology, risk factors and possible interventions in the early years: Dutch cohort research]
Insights
Pregnancy and early childhood factors significantly influence psychiatric disorder development. Identifying these risks aids future research and interventions for child mental health.
Area of Science:
- Developmental psychology
- Child psychiatry
- Public health
Background:
- Psychiatric disorders arise from multiple contributing factors.
- Understanding early-life influences is crucial for mental health.
- Early identification of risks can inform preventative strategies.
Purpose of the Study:
- To examine pregnancy and early childhood factors linked to psychiatric problems.
- To synthesize findings from major Dutch child cohort studies.
Main Methods:
- Review of findings from four large-scale Dutch child cohort studies.
- Analysis of risk factors during pregnancy and early developmental stages.
Main Results:
- Identified specific risk factors during pregnancy and early childhood.
- Described mechanisms contributing to psychopathology development.
- Highlighted the role of environmental and biological factors.
Conclusions:
- Identified risk factors and mechanisms offer targets for future research.
- Findings can guide the development of prevention and intervention programs.
- Early life experiences are critical determinants of long-term mental health.
Abstract:
Background Multiple factors contribute to the development of psychiatric disorders. Aim To discuss factors in pregnancy and early childhood that contribute to the development of psychiatric problems. Method Overview of the findings of four major Dutch child cohorts. Results Based on findings of four major Dutch child cohorts, we describe risk factors during pregnancy and early childhood that contribute to the development of psychopathology. Conclusion The identified risk factors and mechanisms can serve as targets for follow-up research, prevention, and intervention. Tijdschrift voor psychiatrie 63(2021)2, 107-110.
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