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Diagnosis for COVID-19: current status and future prospects
Md Alamgir Kabir1,2, Rajib Ahmed3, Sheikh Muhammad Asher Iqbal1,2
1Florida Atlantic University, Boca Raton, FL, USA.
Expert Review of Molecular Diagnostics
|February 23, 2021
Summary
Accurate molecular diagnosis of SARS-CoV-2 (the virus that causes COVID-19) is crucial for managing the pandemic. This review covers diagnostic evolution, market analysis, and strategies for confronting the global health emergency.
Area of Science:
- Molecular diagnostics
- Virology
- Public health
Background:
- COVID-19, caused by SARS-CoV-2, rapidly became a global pandemic.
- Prompt diagnosis, isolation, and treatment are key to managing the COVID-19 crisis.
- International travel significantly contributed to the virus's widespread transmission.
Purpose of the Study:
- To review the evolution of SARS-CoV-2 detection methods.
- To analyze the performance and market of commercial diagnostic products.
- To identify strategies for addressing the ongoing global health emergency.
Main Methods:
- Discussion of phenotype, structural, and molecular evolution of recognition elements and primers.
- Evaluation of laboratory and point-of-care detection methods.
- Market analysis of commercial diagnostic products and their performance.
Main Results:
- The review covers the development and application of various diagnostic tools for SARS-CoV-2.
- Performance of commercial diagnostic products is assessed.
- Insights into confronting the public health emergency are provided.
Conclusions:
- Developing more effective, rapid, and early diagnostic devices is essential.
- Investment in clinically relevant, multiplexed, and scalable detection tools is recommended for testing laboratories.
- Enhanced diagnostic capabilities are critical for managing pandemic-level outbreaks.
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