Cold atmospheric plasma as an interface biotechnology for enhancing surgical implants

Area of Science:

• Plasma medicine
• Biotechnology
• Biomaterials science

Background:

• Cold atmospheric plasma (CAP) is researched for direct cell/tissue treatment.
• Indirect applications of CAP in plasma medicine are gaining attention.
• Surgical implants require enhanced performance at the implant-tissue interface.

Purpose of the Study:

• To review recent advances in CAP-assisted implant-based therapy.
• To explore CAP's role in interface biotechnology for surgical implants.
• To identify opportunities and challenges in translating implant science to plasma medicine.

Main Methods:

• Review of preclinical research on CAP-assisted implant therapies.
• Analysis of CAP's application in surface modification, coating deposition, and drug delivery for implants.
• Examination of chemical, physical, mechanical, electrical, and pharmacological processes at the implant-tissue interface.

Main Results:

• CAP can ameliorate surgical implants via interface biotechnology strategies.
• Understanding interface processes is crucial for effective CAP application.
• CAP shows potential for enhancing implant-tissue integration across surgical specialties.

Conclusions:

• CAP presents unique opportunities for advancing implant-based therapies.
• Translating implant science to plasma medicine requires addressing specific challenges.
• Further research is needed to fully realize CAP's potential in surgical implants.