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Published on: December 19, 2020
Micronodular pattern organising pneumonia mimicking miliary lung disease: a rare radiological presentation
David Ng1,2, Garun Hamilton3, Eric Hu4
1Department of Diagnostic Imaging, Monash Health, Clayton, Victoria, Australia davidng132@gmail.com.
Abstract:
Organising pneumonia (OP) is an interstitial lung disease characterised by granulation tissues in alveoli and alveolar ducts. Typical imaging findings are migratory airspace opacities with peripheral or peribronchovascular distribution. Diffuse micronodular OP (MNOP) is a rare imaging manifestation, which has imaging differential diagnosis of endobronchial infection such as tuberculosis, hypersensitivity pneumonitis and respiratory bronchiolitis. Although clinical and ancillary radiological findings may aid in refining the differential diagnosis, histopathological assessment is frequently required for this rare presentation due to implications of treatment and prognosis. We report a case of MNOP and performed a review of the literature.
Insights
Diffuse micronodular organizing pneumonia (MNOP) is a rare lung condition. Diagnosis often requires biopsy due to overlapping symptoms with other lung diseases.
Area of Science:
- Pulmonology
- Radiology
- Pathology
Background:
- Organizing pneumonia (OP) is an interstitial lung disease.
- Typical OP imaging shows migratory opacities.
- Diffuse micronodular OP (MNOP) is a rare variant.
Observation:
- This case presents a rare imaging manifestation of MNOP.
- Differential diagnoses include tuberculosis and hypersensitivity pneumonitis.
- Clinical and radiological findings can suggest MNOP.
Findings:
- MNOP presents with diffuse micronodular opacities.
- Histopathological assessment is often necessary for definitive diagnosis.
- This study reviews a case of MNOP and relevant literature.
Implications:
- Accurate diagnosis of MNOP is crucial for appropriate treatment and prognosis.
- Understanding rare OP variants improves diagnostic accuracy.
- Further research into MNOP imaging and pathology is warranted.
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