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A morphological evidence for monosynaptic projections from the nucleus tegmenti pedunculopontinus pars compacta (TPC)
H Tokuno1, T Moriizumi, M Kudo
1Department of Anatomy, School of Medicine, Kanazawa University, Japan.
Neuroscience Letters
|February 15, 1988
Abstract:
Electrolytic lesion was placed in the nucleus tegmenti pedunculopontinus pars compacta (TPC) in cats, which were injected simultaneously with horseradish peroxidase (HRP) into the caudate nucleus (Cd). After a survival period of 4 days, the substantia nigra pars compacta (SNC) was examined electron microscopically. Degenerating axon terminals were found to make asymmetric synaptic contacts on dendrites of SNC neurons which were retrogradely labeled with HRP. Thus, TPC neurons were indicated to project monosynaptically to SNC neurons which sent their axons to the Cd.