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Characterization of the novel HLA-C*01:02:56 and HLA-C*01:02:57 alleles by sequencing-based typing

Xuan You1,2, Yanmin He1,2, Bing Dai1,2

  • 1HLA typing laboratory, Blood Center of Zhejiang Province, Hangzhou, Zhejiang Province, China.

HLA
|February 24, 2021
PubMed

Keywords:
HLA-C*01:02:56HLA-C*01:02:57novel allelepolymerase chain reaction sequence-based typing

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Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...
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