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The Full Genomic Sequence of the HLA-DRB1*15:140 Allele Identified Using PacBio Sequencing

Hongwei Li1,2, Long Yang3, Zhongyang Shen1

  • 1The First Central Clinical School, Tianjin Medical University, Tianjin, China.

HLA
|October 23, 2026
PubMed

Abstract:

We report the full genomic sequence of the HLA-DRB1*15:140 allele.

Keywords:
DRB1*15:140HLAPacBio sequencingfull genomic sequence

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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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