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Updated: Nov 16, 2025

Whole-brain Segmentation and Change-point Analysis of Anatomical Brain MRI—Application in Premanifest Huntington's Disease

Whole-brain Segmentation and Change-point Analysis of Anatomical Brain MRI—Application in Premanifest Huntington's Disease

Published on: June 9, 2018

Reliability of Changes in Brain Volume Determined by Longitudinal Voxel-Based Morphometry.

Hidemasa Takao¹, Shiori Amemiya¹, Osamu Abe¹

¹Department of Radiology, Graduate School of Medicine, University of Tokyo, Tokyo, 113-8655, Japan.

Journal of Magnetic Resonance Imaging : JMRI

|February 24, 2021

Summary

Longitudinal voxel-based morphometry (VBM) shows good to excellent reliability for assessing brain changes in healthy elderly, mild cognitive impairment (MCI), and Alzheimer's disease (AD) patients over two years. Reliability may be influenced by disease-related factors like head motion.

Failed At:

2026-06-19T13:48:14.994982+00:00

Keywords:

Alzheimer's disease magnetic resonance imaging mild cognitive impairment reproducibility stability test-retest reliability

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