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Updated: Nov 16, 2025
Author Spotlight: Advancing Facial Rejuvenation Therapy with Post-Laser Salicylic Acid Application
Published on: September 27, 2024
Histological and immunohistochemical changes in facial skin treated with combined ablative and non-ablative laser
Natalia A Shanina1, Alexander V Patrushev1, Anže Zorman2
1S. M. Kirov Military Medical Academy, Sankt Petersburg, Russian Federation.
Background:
Facial skin rejuvenation is a highly sought after procedure. Different materials, energy-based devices and techniques have been shown to offer good results in facial rejuvenation.
Aims:
The aim of this study was to evaluate the macroscopic and histological and immunohistochemical changes in facial skin treated with a combined laser therapy.
Patients/Methods:
Fourteen patients aged from 38 to 59 years were included in the study. Two different wavelengths (2940 and 1064 nm) were used in this four-step procedure.
Results:
Significant improvement according to classification for age-related changes in all areas of the face was achieved. There were also significant structural changes in the epidermis and dermis, confirmed with histology and immunohistochemistry.
Conclusion:
The dual-wavelength protocol has been found to provide excellent results for facial rejuvenation.
