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Concomitant Use of Botulinum Toxin and Super Long Nd:YAG Laser
1Medilase d.o.o, Ljubljana, Slovenia.
Background:
Botulinum toxin is a widely utilized minimally invasive therapeutic option with minimal downtime and a low risk of serious complications. The long pulse Nd:YAG laser treatment (PIANO) has been utilized in recent years for skin rejuvenation and tightening, body shaping, and transdermal lipolysis through bulk heating of the tissue. The heat-labile bond between the heavy and light chains of botulinum toxin could be affected by laser bulk heating.
Aims:
This case series aims to clinically evaluate the efficacy of botulinum toxin when used in conjunction with PIANO 1064 nm bulk heating.
Patients/Methods:
This case series included two patients who underwent standard hyperhidrosis treatment with botulinum toxin and then single-sided concomitant long-pulsed Nd:YAG laser treatment.
Results:
The iodine-starch test revealed no differences between the two areas at follow-up visits.
Conclusion:
This small study corroborates the findings of other research indicating that long-pulsed 1064 nm Nd:YAG laser treatment does not affect the efficacy of botulinum toxin.

