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Updated: Nov 16, 2025

Single-stage Dynamic Reanimation of the Smile in Irreversible Facial Paralysis by Free Functional Muscle Transfer
Published on: March 1, 2015
[Recurrent peripheral facial nerve palsy]
Belén Gómez-González1, Javier González-García, Ángela Gómez-Farpón
1Hospital Universitario de Cabueñes, Servicio de Pediatría, Gijón, España. belengomezglez@gmail.com.
Background:
Melkersson-Rosenthal syndrome is a rare disorder that is characterized, in its full form, by recurrent facial nerve palsy, fissured tongue, and orofacial edema. Most cases present as oligosymptomatic or monosymptomatic forms. Its etiology is still unknown and its course is chronic and it may be progressive.
Case Report:
We present the case of a nine-year-old girl with recurrent episodes of peripheral facial nerve palsy. During the study, lip edema, benign migratory glossitis, and angular cheilitis were observed, which is why a clinical diagnosis of Melkersson-Rosenthal syndrome was made.
Conclusions:
This syndrome must be considered in the differential diagnosis with the presence of acute peripheral facial nerve palsy and/or facial edema due to its behavior and progressive evolution.
Insights
Melkersson-Rosenthal syndrome, a rare condition causing facial palsy and swelling, requires consideration in diagnoses. Early recognition is key for managing this progressive disorder.
Area of Science:
- Neurology
- Dermatology
- Genetics
Background:
- Melkersson-Rosenthal syndrome is a rare neurological disorder.
- Characterized by facial nerve palsy, fissured tongue, and orofacial edema.
- Etiology is unknown; the course is chronic and potentially progressive.
Observation:
- A case of a nine-year-old girl with recurrent peripheral facial nerve palsy.
- Observed symptoms included lip edema, benign migratory glossitis, and angular cheilitis.
- Clinical diagnosis of Melkersson-Rosenthal syndrome was established.
Findings:
- The patient presented with oligosymptomatic Melkersson-Rosenthal syndrome.
- Recurrent facial nerve palsy and orofacial edema were key indicators.
- Associated findings included glossitis and cheilitis.
Implications:
- Melkersson-Rosenthal syndrome should be considered in differential diagnoses.
- Crucial for cases presenting with acute peripheral facial nerve palsy or facial edema.
- Understanding its progressive nature aids in patient management.
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