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Implantation of Total Artificial Heart in Congenital Heart Disease
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Neurologic complications of congenital heart disease in adults

Sarah A Goldstein1, Larry B Goldstein2

  • 1Department of Medicine, Division of Cardiology, Duke University, Durham, NC, United States.

Handbook of Clinical Neurology
|February 26, 2021
PubMed

Insights

Adults with congenital heart disease (CHD) face varied neurological issues, including stroke and cognitive impairment. Specialized multidisciplinary care is crucial for managing these complex lifelong conditions.

Area of Science:

  • Cardiology
  • Neurology
  • Adult Congenital Heart Disease

Background:

  • Congenital heart disease (CHD) comprises birth-related cardiovascular structural abnormalities.
  • Improved pediatric treatments result in a growing adult population with CHD.

Purpose of the Study:

  • To outline the neurological complications in adults with CHD.
  • To emphasize the need for integrated care approaches.

Main Methods:

  • Review of existing literature on neurological complications in adult CHD patients.
  • Analysis of risk factors including congenital defects, surgical history, and age-related comorbidities.

Main Results:

  • Adults with CHD exhibit increased risks of stroke, neurodevelopmental disorders, cognitive deficits, psychiatric conditions, and epilepsy.
  • Neurological risks stem from intrinsic heart defects, surgical interventions, and age-related atherosclerosis.

Conclusions:

  • Neurological complications are a significant concern for adults with CHD.
  • Collaborative, multidisciplinary care involving neurologists and adult CHD cardiologists is essential for optimal patient outcomes.

Keywords:
AutismBrain hemorrhageCognitionCongenital heart diseaseEpilepsyIschemic stroke

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