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Improving medication adherence in hypertensive patients: A scoping review
Simão Pinho1, Mariana Cruz1, Filipa Ferreira2
1Department of Biomedicine, Faculty of Medicine, University of Porto, Alameda Hernâni Monteiro, 4200-319 Porto, Portugal.
Preventive Medicine
|February 26, 2021
Summary
Improving medication adherence for hypertension is crucial. This study provides a clear overview and a new evidence-based categorization of interventions for hypertensive patients, aiding future research and clinical practice.
Area of Science:
- Cardiology
- Pharmacology
- Health Services Research
Background:
- Medication adherence is a significant challenge in managing arterial hypertension.
- Despite numerous interventions, efforts to improve adherence have often been disorganized and frustrating.
Purpose of the Study:
- To conduct a scoping review of medication adherence interventions in hypertensive patients.
- To develop an evidence-based categorization of these interventions for a clearer overview.
Main Methods:
- The review followed the PRISMA-ScR statement, searching MEDLINE and Web of Science until August 17, 2020.
- Analyzed 45 included articles regarding study design, participant characteristics, adherence strategies, outcomes, and measurement tools.
- Interventions were categorized using a novel evidence-based system derived from machine learning conceptual clustering.
Main Results:
- A total of 45 articles were included after screening 2994 non-duplicate studies.
- Evaluated medication adherence, blood pressure outcomes, and adherence measurement tools.
- Developed a new, evidence-based categorization tool for adherence interventions.
Conclusions:
- This work offers a comprehensive overview of the research field on medication adherence interventions in hypertension.
- The novel categorization tool facilitates more informed and efficient future research.
- Provides valuable insights for clinicians managing antihypertensive therapy adherence.
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