Related Experiment Video

Updated: Nov 16, 2025

Assessing Urinary Tract Junction Obstruction Defects by Methylene Blue Dye Injection
06:05

Assessing Urinary Tract Junction Obstruction Defects by Methylene Blue Dye Injection

Published on: October 12, 2017

15.9K

Urinary tract imaging in infants with spina bifida: a selective approach to a baseline DMSA

Cascio S1, M Doyle2, O Mc Mahon2

  • 1Department of Paediatric Urology, Children's Health Ireland at Temple Street, Dublin, Ireland; University College Dublin, Ireland.

Journal of Pediatric Urology
|February 27, 2021
PubMed

Insights

Early videourodynamic studies (VUD) in infants with spina bifida (SB) can identify vesico-ureteral reflux (VUR) and bladder dysfunction. A selective DMSA scan approach, based on VUR or febrile UTIs, avoids unnecessary scans in SB patients.

Area of Science:

  • Pediatric Urology
  • Nephrology
  • Neurology

Background:

  • Infants with spina bifida (SB) require careful renal investigation post-birth.
  • Current guidelines recommend baseline DMSA scans and Voiding Cystourethrogram (VCUG) or Videourodynamic (VUD) studies early in life.

Purpose of the Study:

  • To evaluate the outcomes of renal investigations in infants with SB within their first year of life.
  • To determine the necessity of early DMSA scans in managing SB patients.

Main Methods:

  • Review of all renal imaging, including Renal and Bladder Ultrasound (RBUS), VCUGs, VUDs, and DMSA scans.
  • Two independent assessors evaluated the outcomes of these investigations in 70 spina bifida patients.

Main Results:

  • Early VUD identified vesico-ureteral reflux (VUR) in 16% of patients and provided detailed bladder function data.
  • DMSA scans detected renal scarring in 6% of patients, with most having a history of febrile UTIs or VUR.

Conclusions:

  • The study supports recent EUA/ESPU guidelines recommending early VUD or VCUG in infants with SB.
  • A selective DMSA scan approach for SB patients with febrile UTIs or VUR is effective and avoids unnecessary scans.
Abstract

Keywords:
PaediatricsSpinal dysraphismUltrasonographyUrology

More Related Videos

Ultrasonography of the Adult Male Urinary Tract for Urinary Functional Testing05:25

Ultrasonography of the Adult Male Urinary Tract for Urinary Functional Testing

Published on: August 14, 2019

19.6K
State of the Art Cranial Ultrasound Imaging in Neonates10:02

State of the Art Cranial Ultrasound Imaging in Neonates

Published on: February 2, 2015

25.2K

Related Concept Videos

Imaging Studies IV: Magnetic Resonance Imaging01:27

Imaging Studies IV: Magnetic Resonance Imaging

Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
121
Imaging Studies V: Intravenous Urography and Retrograde Pyelography01:22

Imaging Studies V: Intravenous Urography and Retrograde Pyelography

IntroductionIntravenous Urography (IVU) and Retrograde Pyelography (RP) are important diagnostic imaging techniques used to evaluate the urinary system. These methods help identify structural abnormalities, obstructions, and functional issues in the kidneys, ureters, and bladder. Both procedures use iodine-based contrast media to enhance the visibility of urinary tract structures on X-ray images, though they differ in their methods and indications.1. Intravenous Urography (IVU)Intravenous...
508
Imaging Studies VI: Voiding Cystourethrography and Cystography01:22

Imaging Studies VI: Voiding Cystourethrography and Cystography

Voiding Cystourethrography (VCUG) and Cystography are specialized radiographic procedures used to examine the structure and function of the bladder and urethra.Voiding Cystourethrography (VCUG)A Voiding Cystourethrogram (VCUG) is a diagnostic imaging procedure that assesses the anatomy and function of the lower urinary tract. It focuses on the bladder, bladder neck, and urethra, helping detect abnormalities such as vesicoureteral reflux (VUR)—the backward or reverse flow of urine into the...
455
Imaging Studies II: Ultrasonography01:24

Imaging Studies II: Ultrasonography

IntroductionUltrasonography, or renal ultrasound, is a noninvasive medical imaging technique that uses high-frequency sound waves to visualize the kidneys, ureters, bladder, and surrounding tissues.Indications for Urinary System UltrasonographyUrinary system ultrasonography is indicated in various clinical scenarios, such as:Kidney Stones (Urolithiasis): To detect and monitor the size and presence of kidney or urinary tract stones.Hydronephrosis: To assess the dilation of the renal pelvis and...
133
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
126
Imaging Studies I: Kidney, Ureter, and Bladder Studies01:28

Imaging Studies I: Kidney, Ureter, and Bladder Studies

Kidney, Ureter, and Bladder (KUB) StudiesKidney, Ureter, and Bladder (KUB) studies are standard diagnostic imaging procedures used to assess the anatomy of the urinary system. They are commonly utilized for patients experiencing abdominal pain or urinary symptoms. By using a simple X-ray of the abdomen, KUB studies can reveal structural and pathological abnormalities within the kidneys, ureters, and bladder. These studies are particularly valuable in diagnosing kidney stones, urinary...
105