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Updated: Nov 16, 2025

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
Neonatal sleep development and early learning in infants with prenatal opioid exposure
Nicole A Heller1, Hira Shrestha2, Deborah G Morrison3
1Department of Psychology, Siena College, Loudonville, NY, United States.
Insights
Poor neonatal sleep in at-risk infants is both a result of perinatal risks and a predictor of later attention and cognitive issues. Early interventions addressing sleep are crucial for developmental outcomes.
Area of Science:
- Developmental Psychology
- Neuroscience
- Pediatrics
Background:
- The cumulative risk model suggests multiple factors negatively impact child development.
- These factors include prenatal exposures, prematurity, socioeconomic status, parenting, and sleep.
- Poor neonatal sleep is a significant, yet often overlooked, factor in this model.
Purpose of the Study:
- To examine the interplay between sleep and cognition in at-risk infants within the cumulative risk framework.
- To understand poor neonatal sleep as both an outcome and a predictor of developmental challenges.
- To identify implications and interventions for at-risk maternal-infant dyads.
Main Methods:
- Analysis of at-risk infant and maternal-infant dyad samples.
- Examination of neonatal sleep patterns in relation to other known risk factors.
- Review of existing literature on sleep, cognition, and cumulative risk.
Main Results:
- Poor neonatal sleep is identified as both a consequence of perinatal adversity and a risk factor for cognitive development.
- Specific outcomes associated with poor sleep and cognition in infancy are detailed.
- The relationship between sleep disturbances and other cumulative risks is highlighted.
Conclusions:
- Neonatal sleep is a critical component of the cumulative risk model impacting infant development.
- Interventions targeting sleep in at-risk infants may mitigate negative cognitive and attentional outcomes.
- Further research and clinical attention to infant sleep are warranted.
Abstract:
The aim of this chapter is to examine the role of sleep and cognition in the context of the cumulative risk model examining samples of at-risk infants and maternal-infant dyads. The cumulative risk model posits that non-optimal developmental outcomes are the result of multiple factors in a child's life including, but not limited to, prenatal teratogenic exposures, premature birth, family socioeconomic status, parenting style and cognitions as well as the focus of this volume, sleep. We highlight poor neonatal sleep as both an outcome of perinatal risk as well as a risk factor to developing attentional and cognitive capabilities during early childhood. Outcomes associated with and contributing to poor sleep and cognition during infancy are examined in relation to other known risks in our clinical population. Implications of this research and recommendations for interventions for this population are provided.
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