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Updated: Nov 15, 2025

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Published on: March 15, 2022
Antiplatelet Drugs for Neurointerventions: Part 2 Clinical Applications
Samuel Pearce1,2, Julian T Maingard3,4, Hong Kuan Kok4,5
1Department of Radiology, Western Health, 160 Gordon St, 3011, Footscray, Victoria, Australia. s.pearce89@gmail.com.
Abstract:
Endovascular techniques have expanded to include balloon and stent-assistance, flow diversion and individualized endovascular occlusion devices, to widen the treatment spectrum for more complex aneurysm morphologies. While usually well-tolerated by patients, endovascular treatment of intracranial aneurysms carries the risk of complications, with procedure-related ischemic complications being the most common. Several antiplatelet agents have been studied in a neurointerventional setting for both prophylaxis and in the setting of intraprocedural thrombotic complications. Knowledge of these antiplatelet agents, evidence for their use and common dosages is important for the practicing neurointerventionist to ensure the proper application of these agents.Part one of this two-part review focused on basic platelet physiology, pharmacology of common antiplatelet medications and future directions and therapies. Part two focuses on clinical applications and evidence based therapeutic regimens.
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