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Updated: Nov 15, 2025

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Real-time Imaging of Single Engineered RNA Transcripts in Living Cells Using Ratiometric Bimolecular Beacons
Published on: August 6, 2014
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Accelerated DNA tetrahedron-based molecular beacon for efficient microRNA imaging in living cells
Chao Xing1, Ziyi Chen, Yuhong Lin
1Fujian Key Laboratory of Functional Marine Sensing Materials, Center for Advanced Marine Materials and Smart Sensors, Minjiang University, Fuzhou 350108, P. R. China. chaoxing@mju.edu.cn wangjun2@mju.edu.cn.
Abstract:
Herein, we develop an accelerated DNA tetrahedron based molecular beacon for efficient detection and imaging of miRNA in living cells. Our study provides an improved strategy for fluorescence amplified RNA imaging in early clinical diagnosis.

