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[Chlamydia trachomatis perihepatitis].

J P Ducroix1, A Smail, F Eb

  • 1Service de Médecine Interne, Hospitalier Régional, d'Amiens.

Annales De Medecine Interne
|January 1, 1988
PubMed
Summary
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Chlamydia trachomatis can cause perihepatitis in young women, often presenting as biliary pain without obvious genital infection. Prompt antibiotic treatment with Cyclins or Macrolids effectively resolves symptoms.

Area of Science:

  • Gynecology
  • Infectious Diseases
  • Hepatology

Context:

  • Perihepatitis, inflammation of the liver capsule, is often associated with pelvic inflammatory disease.
  • Chlamydia trachomatis is a common cause of sexually transmitted infections.

Purpose:

  • To investigate the clinical presentation, diagnosis, and treatment of perihepatitis caused by Chlamydia trachomatis.

Summary:

  • Fifteen cases of perihepatitis in young women (mean age 29.3 years) were analyzed.
  • Genital Chlamydia trachomatis infection was not always clinically apparent or reported.
  • Patients primarily presented with biliary-type pain, sometimes accompanied by pelvic pain.
  • Diagnosis was suspected with normal routine investigations and confirmed by positive serology (antibody titer > 1/64) via micro-immunofluorescence.

Related Experiment Videos

  • Treatment with Cyclins or Macrolids resulted in symptom regression within the first week.

    • Impact:

    • Highlights the importance of considering Chlamydia trachomatis in young women with unexplained upper abdominal pain.
    • Demonstrates the efficacy of antibiotic therapy in managing Chlamydia-induced perihepatitis.
    • Suggests that serological testing is crucial for diagnosing Chlamydia trachomatis perihepatitis when genital infection is not evident.