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Updated: Nov 15, 2025

Visualization and Quantification of Brown and Beige Adipose Tissues in Mice using [18F]FDG Micro-PET/MR Imaging
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Visualization and Quantification of Brown and Beige Adipose Tissues in Mice using [18F]FDG Micro-PET/MR Imaging

Published on: July 1, 2021

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Clinical imaging of marrow adiposity

Mohamed Jarraya1, Miriam A Bredella1

  • 1Massachusetts General Hospital, Department of Radiology, Harvard Medical School, Boston, MA, USA.

Best Practice & Research. Clinical Endocrinology & Metabolism
|March 2, 2021
PubMed

Research examining bone marrow adipose tissue (BMAT) has rapidly expanded during the last two decades, leading to advances in knowledge on the role of BMAT in the pathogenesis of bone loss and endocrine disorders. Clinical imaging has played a crucial role for the in vivo assessment of BMAT, allowing non-invasive quantification and evaluation of BMAT composition. In the present work, we review different imaging methods for assessing properties of BMAT. Our aim is to review conventional magnetic resonance imaging (MRI), water-fat imaging, and single-voxel proton magnetic resonance spectroscopy (1H-MRS), as well as computed tomography (CT)-based techniques, including single energy and dual energy CT. We will also discuss the clinical applications of these methods in type 2 diabetes mellitus, obesity and anorexia nervosa.

Keywords:
bone marrow adipose tissuedual energy computed tomographyimagingmagnetic resonance imagingproton magnetic resonance spectroscopy

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