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[Value of esogastroduodenal endoscopy with staged biopsies in children with Crohn's disease]
L M Mashako1, J F Mougenot, E Sonsino
1Service de Gastro-entérologie et Nutrition pédiatrique, Hôpital Bretonneau, Paris.
Insights
Upper gastrointestinal endoscopy with biopsies aids in diagnosing Crohn disease (CD) in children. This method proved crucial, being the sole diagnostic tool in 4 cases, highlighting its systematic importance.
Area of Science:
- Pediatric Gastroenterology
- Gastrointestinal Pathology
Abstract:
An upper gastrointestinal endoscopy with multiple biopsies was performed in 19 children suspected of Crohn disease (CD) who had also undergone X-ray investigations and colonoscopy with multiple biopsies. Biopsies were performed in pathological and/or normal mucous areas. Upper gastrointestinal endoscopy showed macroscopic changes in 7 children (37%). Histologic examinations of the upper gastrointestinal tract were normal or showed only non specific changes in 12 cases (63%). Histopathologic changes specific for CD were found in 7 cases (37%), while specific histologic changes were identified at the rectal or colic level in 3 of these 7 cases only. Thus, upper gastrointestinal endoscopy with multiple biopsies was most useful for the diagnosis of CD, since it was the only diagnostic means in 4 cases. It should be systematically performed when CD is suspected.