Related Experiment Video
Updated: Nov 15, 2025
09:47
Isolation, Processing and Analysis of Murine Gingival Cells
Published on: July 2, 2013
19.5K
[A woman with gingival enlargement]
D A R Castelijn1,2, M J Wondergem1, D M Heijink1
1Amsterdam UMC, locatie VUmc, afd. Hematologie, Amsterdam.
Nederlands Tijdschrift Voor Geneeskunde
|March 2, 2021
Summary
Rapidly worsening gum overgrowth in a 65-year-old patient was linked to acute myelomonocytic leukemia. Successful leukemia treatment led to the resolution of gingival enlargement symptoms.
Area of Science:
- Hematology
- Oral Medicine
- Oncology
Background:
- Gingival enlargement can manifest due to various factors including medications, infections, and systemic conditions.
- Rapidly progressive and generalized gingival overgrowth warrants consideration of hematological malignancies.
Observation:
- A 65-year-old female presented with diffuse and rapidly progressing gingival enlargement.
- Initial differential diagnoses for gingival hyperplasia were considered.
Findings:
- Blood work confirmed the diagnosis of acute myelomonocytic leukemia (AMML).
- The gingival enlargement was directly correlated with the presence of AMML.
Implications:
- This case highlights the importance of considering leukemia in the differential diagnosis of rapidly progressing gingival enlargement.
- Effective treatment of the underlying acute myeloid leukemia resulted in the complete resolution of oral symptoms.
- Early recognition and management of hematological disorders can significantly impact oral health outcomes.
Related Concept Videos
01:15Teeth
1.2K
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
1.2K
01:26Tonsillitis II: Management
255
This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.
255
01:26Assessment of the Mouth
723
A thorough mouth assessment, including inspection and palpation of the lips, gums, tongue, tonsils, uvula, and pharynx, is crucial in detecting potential health issues. Diseases ranging from oral cancer to systemic conditions like diabetes could be identified early through careful oral examination. This article provides a detailed guide on conducting a comprehensive mouth assessment.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
723
01:15External Female Genitals
19.6K
The vulva encompasses the external structures of the female reproductive system. At the forefront is the monpubis, a cushion of fatty tissue atop the pubic bone. Once puberty sets in, this area typically grows hair. Extending from just behind the mons pubis are the labia majora (labia = 'lips'; majora = 'larger'), which are larger skin fs olds coated with hair. Nestled within are the labia minora (labia = 'lips'; minora = 'smaller'), which are thinner, more...
19.6K
01:24Disorders of the Female Reproductive System
3.6K
The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
3.6K
01:27Signs of Puberty
895
Puberty is a critical phase, typically beginning between the ages of 8 and 13 in girls and 9 and 14 in boys, though timing can vary based on genetics, environmental factors, and overall health. This period is characterized by the development of secondary sexual characteristics and the attainment of reproductive potential. Endocrine changes underpin puberty, with hormonal surges of Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH) instigated by Gonadotropin-Releasing Hormone (GnRH)...
895