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Radiogenomics in Colorectal Cancer
Bogdan Badic1, Florent Tixier1, Catherine Cheze Le Rest1,2
1National Institute of Health and Medical Research, LaTIM-Laboratory of Medical Information Processing (INSERM LaTIM), UMR 1101, Université Bretagne Occidentale, 29238 Brest, France.
Cancers
|March 3, 2021
Summary
Radiogenomics combines medical imaging (radiomics) and genetic data (genomics) to understand colorectal cancer heterogeneity. This review outlines current research, limitations, and future directions for personalized medicine.
Area of Science:
- Oncology
- Medical Imaging
- Genomics
Background:
- High-throughput technologies advance personalized precision medicine.
- Tumor heterogeneity is characterized by radiomics and genomics, forming the field of radiogenomics.
- Radiogenomics research in colorectal cancer is rapidly evolving.
Purpose of the Study:
- To provide an overview of the current colorectal cancer radiogenomics literature.
- To discuss existing limitations in the field.
- To suggest future research directions.
Main Methods:
- Literature review of radiogenomics studies in colorectal cancer.
- Analysis of image-derived features (radiomics) and genetic profiles (genomics).
Main Results:
- Radiogenomics shows potential for enhancing clinical decision-making in colorectal cancer.
- Existing studies highlight the link between imaging features and genetic alterations.
- The field is rapidly advancing with ongoing research.
Conclusions:
- Radiogenomics is a promising approach for understanding colorectal cancer.
- Addressing current limitations is crucial for future development.
- Further research can enhance personalized treatment strategies.
