Related Experiment Video
Updated: Nov 15, 2025
11:13
Assessment of Viability of Human Fat Injection into Nude Mice with Micro-Computed Tomography
Published on: January 7, 2015
11.4K
Early Fat Grafting for Augmentation in Craniofacial Microsomia
Yoshiaki Sakamoto1, Eric Arnaud2
1Department of Plastic and Reconstructive Surgery, Keio University School of Medicine, Japan.
The Journal of Craniofacial Surgery
|March 3, 2021
Summary
Early fat grafting in infants with craniofacial microsomia effectively camouflages facial asymmetry. This approach offers acceptable outcomes without overcorrection, providing a valuable option for managing soft tissue defects in young patients.
Area of Science:
- Plastic Surgery
- Craniofacial Surgery
- Regenerative Medicine
Background:
- Craniofacial microsomia presents complex hard and soft tissue defects.
- Microvascular free tissue transfers are standard for soft tissue reconstruction post-puberty.
- Early intervention strategies for facial contouring are needed.
Purpose of the Study:
- To evaluate the efficacy of early fat grafting for camouflaging facial asymmetry in infants with craniofacial microsomia.
- To assess the safety and outcomes of fat grafting in this pediatric population.
Main Methods:
- Retrospective case series of five infants with craniofacial microsomia.
- Performed early fat grafting at approximately six months of age.
- Monitored for outcomes related to facial contour symmetry and overcorrection.
Main Results:
- Acceptable aesthetic outcomes were achieved in all five patients.
- No instances of overcorrection were observed.
- Early fat grafting successfully camouflaged facial asymmetry.
Conclusions:
- Early fat grafting is a viable and effective method for improving facial symmetry in infants with craniofacial microsomia.
- This technique offers a safe alternative for soft tissue management before puberty.
- The findings support the use of early fat grafting to address contour deformities in craniofacial microsomia.
