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Relationship Between Melatonin and Cardiovascular Disease

Flora Ozkalayci1, Umut Kocabas2, Betul U Altun3

  • 1Cardiology, Hisar Intercontinental Hospital, Istanbul, TUR.

Cureus
|March 3, 2021
PubMed

Insights

Melatonin may offer cardiovascular benefits by reducing inflammation, a key factor in coronary artery disease (CAD). Further research could establish melatonin

Area of Science:

  • Cardiovascular Science
  • Endocrinology
  • Inflammation Research

Background:

  • Coronary artery disease (CAD) is a major global health concern.
  • Inflammation plays a critical role in the development of atherosclerotic plaques.
  • Melatonin's cardiovascular benefits are recognized but underutilized in clinical practice.

Purpose of the Study:

  • To review the role of melatonin in cardiovascular disease (CVD).
  • To investigate melatonin's impact on CVD risk factors.
  • To highlight the potential of melatonin in cardiovascular health.

Main Methods:

  • Literature search via PubMed, Wikipedia, and Google.
  • Review of existing studies on melatonin and cardiovascular effects.
  • Synthesis of data on melatonin's influence on CVD and risk factors.

Main Results:

  • Inflammation is a significant contributor to atherosclerotic plaque formation.
  • Studies indicate melatonin possesses favorable effects on the cardiovascular system.
  • Melatonin's therapeutic potential in managing CVD and its risk factors is suggested.

Conclusions:

  • Melatonin's anti-inflammatory properties are relevant to cardiovascular protection.
  • Further clinical investigation is warranted to integrate melatonin into CVD management.
  • Melatonin may represent a promising therapeutic agent for cardiovascular health.

Keywords:
cardiovascularcircadian rhythmcoronary artery diseasemelatoninrisk factors

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