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Synthesis of deuterium-labelled elliptinium and its use in metabolic studies

A Gouyette1

  • 1Pharmacologie Clinique (UA147 CNRS, U140 INSERM), Pavillon de Recherche, Institut Gustave-Roussy, Villejuif, France.

Biomedical & Environmental Mass Spectrometry
|March 1, 1988
PubMed

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¹H NMR of Labile Protons: Deuterium (²H) Substitution00:48

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This lesson illustrates the role of deuterium substitution in simplifying the NMR spectrum of compounds comprising labile protons. One method employed is the use of deuterium. Amongst the three isotopes of hydrogen, deuterium (2H) has a nucleus composed of one proton and one neutron. When the D2O solvent is added to a pure dry ethanol solution, its labile proton is substituted with deuterium.