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Updated: Nov 15, 2025

Laser Microdissection Applied to Gene Expression Profiling of Subset of Cells from the Drosophila Wing Disc
Published on: April 30, 2010
Circadian Gene Profiling in Laser Capture Microdissected Mouse Club Cells
Zhenguang Zhang1, Andrew Loudon1
1School of Medical Science, Faculty of Biology, medicine and Health, University of Manchester, Manchester, UK.
Abstract:
Cell heterogeneity is high in tissues like lung. Research conducted on pure population of cells usually offers more insights than bulk tissues, such as circadian clock work. In this protocol, we provide a detailed work flow on how to do circadian clock study by RNA seq in laser capture micro-dissected mouse lung club cells. The method uses frozen tissues and is highly reproduciable.
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